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How Do You Assess Cognitive Function in Neurology?

How Do You Assess Cognitive Function in Neurology?

To uncover the most insightful and reliable methods for assessing cognitive function, we reached out to neurology professionals, including an Assistant Professor of Clinical Neurology. While he highlights the use of code words for awareness testing, we’ve also gathered additional answers to provide a broader perspective. From using code words to measuring brainwave patterns with EEG, here are several methods that experts find particularly effective.

  • Use Code Words for Awareness Testing
  • Observe Brain Activity with Neuroimaging
  • Assess Cognitive Speed with Reaction Time
  • Administer Standardized Cognitive Assessment Batteries
  • Analyze Brain Function with Functional MRI
  • Measure Brainwave Patterns with EEG

Use Code Words for Awareness Testing

As an epileptologist, I frequently utilize two techniques for assessing cognitive function. The first is giving code words to test awareness during a suspected seizure. Code words are simple phrases such as a color and object (e.g., "red dog," "blue truck," or "purple pig"). Code words are easy to remember but impossible to guess. If a patient can recall these code words, recollection suggests retained awareness at the time that the words were said. Intact awareness indicates focal-onset seizure or possibly that the patient is experiencing nonepileptic events. Lack of awareness and failure to recall a code word indicates a generalized seizure or other generalized encephalopathy.

For those patients with medically intractable epilepsy receiving epilepsy surgery evaluation, another technique for extensively assessing cognitive function is neuropsychiatric testing to delineate the functional deficit zone of the brain. The goal of epilepsy surgery is to identify and remove or destroy the epileptogenic zone of the brain, and the functional deficit zone can provide noninvasive concordant data to suggest impactful surgical options. In focal epilepsy, the functional deficit zone is predictable with both lateralizing and localizing features. For example, visual-spatial deficits and visual processing disorders localize well to the nondominant temporal lobe while verbal memory impairment predicts involvement of the dominant temporal lobe.

The degree and localization of neuropsychiatric impairment also can predict what cognitive deficits are possible after surgery or if concordant epilepsy surgery is predicted to cause minimal change to the patient’s neurocognitive profile. With the additional data of the scalp electroencephalogram (EEG) ictal pattern, magnetic resonance imaging (MRI) of the brain, and other functional studies, epileptologists may suggest highly precise and efficacious surgeries for their patients with intractable epilepsy by thoroughly assessing cognitive functions with neuropsychiatric testing.

Derryl Miller
Derryl MillerAssistant Professor of Clinical Neurology, Indiana University and IU Health Physicians

Observe Brain Activity with Neuroimaging

Administering neuroimaging can help observe brain activity by providing detailed images of different brain areas. These images can reveal abnormalities or changes in brain structure. Such techniques include MRI and CT scans, which are non-invasive and widely used in medical practice.

They allow doctors to visualize the brain in high detail and spot potential issues that could affect thinking and memory. To ensure a thorough examination, encourage patients to undergo these neuroimaging procedures when necessary.

Assess Cognitive Speed with Reaction Time

Conducting simple reaction time tests can assess a person’s cognitive function by measuring how quickly they respond to stimuli. These tests are easy to perform and can be done with minimal equipment. By timing how fast someone reacts, doctors can get an idea of how well their brain is working.

Reaction time can indicate changes in mental alertness or processing speed, which are important aspects of cognitive health. Remind patients to participate in these tests as part of their cognitive assessments.

Administer Standardized Cognitive Assessment Batteries

Utilizing standardized cognitive assessment batteries involves administering a series of exercises designed to measure different aspects of thinking. These batteries can evaluate memory, language, problem-solving, and other cognitive skills. Standardized tests provide a reliable way to compare an individual's performance to typical scores.

This comparison can help identify specific areas where the brain may not be functioning well. Motivating patients to engage in these assessments can lead to early detection and treatment of cognitive issues.

Analyze Brain Function with Functional MRI

Employing functional MRI (fMRI) for brain functionality analysis allows researchers to observe brain activity in real time. This technique shows which parts of the brain are active during certain tasks by measuring changes in blood flow. It helps in understanding how different brain regions work together and their roles in cognitive functions.

Functional MRI provides valuable insights, particularly for diagnosing complex neurological conditions. Encourage the use of fMRI for a comprehensive view of brain activity during cognitive tasks.

Measure Brainwave Patterns with EEG

Measuring brainwave patterns with an EEG can provide important information about brain activity and health. Electroencephalography (EEG) records electrical signals from the brain, which can indicate issues like epilepsy or sleep disorders. By analyzing these patterns, doctors can determine if there are any disruptions in normal brain function.

EEG is non-invasive and can be conducted relatively quickly, making it a useful tool in the diagnostic process. Patients should be encouraged to undergo EEG testing to help diagnose and manage cognitive conditions effectively.

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